‘Seven’ Tagged Posts

Seven Weeks on Anti-Depressants (Sertraline) / Vlog #1

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Seven Years After “Charlotte’s Net,” A CBD Therapy for Epilepsy Strikes One Step Nearer to FDA Approval

 

A number of years in the past, individuals who used the cannabis-derived substance cannabidiol (CBD) risked arrest – or had been compelled to maneuver to states similar to Colorado, the place marijuana merchandise are authorized. That has modified as extra states have legalized hashish and marijuana legal guidelines have been relaxed. This month, the FDA took a big step ahead on this difficulty by recommending approval for the primary CBD medicine from a significant pharmaceutical agency, which is meant to deal with signs of a particular type of epilepsy referred to as Dravet Syndrome.

In 2011, the Stanleys, seven brothers residing in Colorado, developed a hybrid pressure by crossing hashish with industrial hemp, leading to a product that was wealthy in CBD, however low in tetrahydrocannabinol (THC). The latter, after all, is the biochemical that creates the “excessive” for leisure customers, whereas the previous doesn’t. ‘’

CBD does, nonetheless, present quite a few medical advantages. This was actually the case for younger Charlotte Figi, who had suffered extreme epileptic seizures since she was an toddler. It was the Stanley pressure, finally dubbed “Charlotte’s Net,” that just about stopped her seizures altogether.

Now, a significant UK-based drug producer, GW Prescribed drugs, is making an attempt to enter the prescription drug market with its personal model of “Charlotte’s Net.” The corporate submitted a New Drug Software (NDA) final fall. Final week, 13 members of the FDA advisory committee unanimously voted to suggest full approval for the product referred to as Epidiolex, after medical research confirmed a constructive benefit-risk profile.

Over a 14-week medical trial, Epidiolex was proven to be twice as efficient in controlling epileptic seizures in kids who got the drug in comparison with these within the management group. The brand new medicine could be the primary cannabis-based prescription medicine to get FDA approval if the company follows the committee’s suggestion.

GW Prescribed drugs manufactures the same drug, referred to as Sativex, which is accredited in a number of European international locations for the therapy of involuntary muscular contractions symptomatic of a number of sclerosis. That medicine is a hashish extract containing equal components THC and CBD, and isn’t obtainable within the US. Different drug corporations have provide you with medicines primarily based on artificial compounds much like CBD. Epidiolex is basically a pure CBD extract.

Right here is the rub: if accredited and delivered to the market, the worth tag for Epidiolex might be as a lot as $ 60,000 a 12 months, in keeping with monetary analysts (GW Prescribed drugs has declined to remark). Then again, CBD merchandise at present obtainable at marijuana retailers will be bought for as little as $ 100 per 30 days. After all, FDA approval might imply that the price of Epidiolex could be lined by medical insurance coverage.

GW Pharmaceutical CEO Justin Grover factors out that their product “is the topic of rigorous and intense manufacturing controls. Sufferers have the reassurance that the product is what we are saying it’s and what they assume it’s.” Many people who find themselves already treating their epileptic kids efficiently with CBD merchandise are understandably skeptical, given Large Pharma’s observe report of promoting dangerous merchandise and a historical past of value gouging. One mother or father interviewed within the New York Instances stated, “My child’s steady. I’m not touching it. I don’t want a double-blind placebo-controlled research to know one thing [works].”

The seven major markets for Alzheimer’s disease is expected to be Worth $ 7800000000 to 2010

 

(openPR) 6 April 2006

Research and Markets (http://www.researchandmarkets.com/reports/c35223) has announced the addition of the Jain Pharma Biotech report: Alzheimer’s disease – new drugs, markets and businesses realize their offer

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Profiles of 139 companies in developing diagnostics and therapeutics for Alzheimer’s disease are involved presented along with their collaborations. The bibliography contains over 500 publications that are cited in the report. The report is supplemented with 39 tables and 11 illustrations.

Alzheimer’s disease remains a challenge in management. With increased nearly 8 million sufferers from this condition in the seven major markets around the world and expected in the future. Considerable research is underway to understand the pathogenesis of the disease and find a cure. The only medication currently approved acetylcholinesterase inhibitors but not correct the basic pathology of the disease, beta-amyloid deposits and neurofibrillary tangles. Several new approaches emphasize neuroprotection as well.

early diagnosis of Alzheimer’s disease is an important first step in management. Several biomarkers in cerebrospinal fluid, blood and urine can detect the disease. They are a valuable aid to the clinical examination and neuropsychological tests, which are the main diagnostic methods, supplemented by imaging techniques. Genotyping, especially of ApoE gene alleles is also useful in the assessment of cases and planning management.

The current management of Alzheimer’s disease is reviewed and includes a multidisciplinary approach. Acetylcholinesterase inhibitors are mostly a symptomatic treatment but some claims are has a neuroprotective effect. Currently the only approved neuroprotective therapy in is memantine. The management of these patients also require neuroleptics for aggressive behavior and antidepressants. There is an emphasis on the early stage of mild cognitive impairment and early institution of neuroprotective measures. The value of mental exercise in delay of Alzheimer’s disease.

acknowledged

research in Alzheimer’s disease still aims to unravel the basic pathological mechanisms. Animal models are important for research, particularly in testing some of the possible therapeutic approaches. There are significant advances in research on the various centers, some by the National Institute of Aging of the National Institutes of Health. is financed

Over 200 different compounds are in various stages of development for the treatment of Alzheimer’s disease. These are classified and described. There are non-pharmacological approaches such as vagal nerve stimulation and cerebrospinal fluid shunting, which are in clinical trials. performed over 104 clinical trials are run of which 77 still and 27 were discontinued for various reasons.


Alzheimer

market in the seven major markets is worth 6100000000 $ in 2005 and will increase to 7.8 billion U.S. dollars by 2010. The percentage of currently approved drugs specifically for AD is expected in 2005 and $ 3100000000 $ 4,100,000,000 by the year 2010, if all of them stay on the market. Several new therapies are expected to be on the market and estimated the proportions of the different types of approaches for the future until 2015. As background for the markets health economic aspects of care of Alzheimer’s patients and patterns of practice in the seven major markets are examined.


For more information visit http://www.researchandmarkets.com/reports/c35223

Laura Wood

Senior Manager

Research and Markets

press@researchandmarkets.com

Fax: +353 1 4100 980

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Don t be another statistic diabetes, Seven Tips to prevent pre-diabetes from type 2 diabetics Becoming Dave Perry

 

Chicago, Illinois (Nasdaq) 24 August 2006

Diabetes statistics are ugly.

According to the American Diabetes Association, 41 million people in the United States are already diabetic.

And the U.S. Department of Health and Human Services says a majority of 41 million to develop full-blown type 2 diabetes (and a wide range of degenerative diseases), within 10 years.

So how do you reduce your chances of a type-2 diabetes statistics?

Here are seven tips that can help:

# 1 Pay attention to your condition: Test your blood sugar levels, blood pressure and urinary albumin mirco ensure that, when normal, healthy level. Knowing that you already have diabetes are the starting point for minimizing the possibility of progressing to type 2 status. Did you check your blood sugar, especially if you suffer symptoms such as excessive thirst, hunger, blurred vision, frequent urination, a family history of diabetes or obese

# 2 Lose the pounds: overweight or obesity is considered the number one cause of type 2 diabetes. If your body mass index greater than 25 (considered overweight) or 30 (obese), it, AOS time to kill, to lose excess baggage. Drastically cut back on white rice, white bread, potatoes, and high fructose corn syrup sweetened soda drinks. Foods to eat include whole grain breads and cereals, fruits and vegetables

# 3 Get off the couch: Start exercising immediately. A sedentary lifestyle is a major contribution to the development of type 2 diabetes. The combination of diet with moderate exercise (described as 30 minutes a day of physical activity), a loss of 5-10% of body weight leads to a 58% reduction in diabetes.

# 4 Drink a cup of coffee: A recent report by the Archives of Internal Medicine shows that can have a daily dose of Starbucks and other brands contribute to diabetes. The Iowa Women’s Health Study found AOs that the coffee had 22% less chance of occurring type 2 diabetes. Decaffeinated versions had the greatest impact, with positive results across all age and weight classes.

antidepressants stop # 5: A recent study called the Diabetes Prevention Program, researchers found that Äútaking create any kind of anti-depressants did not increase the risk of diabetes, Äú While the results, AOT cause and effect. The study found that a clear link had been established.

# 6 Get the right amount of sleep: Researchers at the New England Research Institutes (together with the Yale School of Medicine researchers) found that sleeping too little or too much increases the risk of diabetes. Six to eight hours of sleep was found to be most beneficial. Those who sleep less or more than that amount were twice as likely to develop diabetes.

# 7 Take Magnesium: A study at Harvard has shown that mineral magnesium had a protective effect against diabetes, improving insulin sensitivity. Sources of magnesium include whole grain bread and complement.

There is no cure for diabetes. But by following these 7 tips can pre-diabetics, the benefits of the resulting lost type 2 problems.

About Proven Results Health http://www.ProvenResultsHealth.com

Proven Results Health is a leading provider of clinically tested to promote all natural supplements for diabetics to diabetics that weight loss and healthy blood sugar levels. For a free 220 page downloadable nutrition and exercise book, Live Longer Now: The First 100 Years of Your Life, please visit the company website AOS

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Contact: Dave Perry, Perry Marketing Communications

Tel: 312.401.1882

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Free Special Report from Johns Hopkins Health Alerts: Seven Keys To Reduce Cholesterol

 

Bethel, CT (PRWEB) March 1, 2007

Johns Hopkins Health Alerts today released an important new Special Report, Seven Keys To Reduce Cholesterol, in order to reduce the risk of heart attack and improve one’s overall health.

The government’s National Cholesterol Education Program (NCEP) estimates that at least 65 million Americans have high cholesterol levels that merit treatment with dietary and other lifestyle changes designed to lower cholesterol. The NCEP also states that as many as 36 million people should be taking cholesterol-lowering medications. Yet only 12 to 15 million of them are currently taking these medications, such as statin drugs (for example, Crestor, Lipitor, Zocor), and many (probably most) are taking too small a dose of statins to reduce cholesterol to safer levels effectively.

As many Americans are now aware, abnormal levels of cholesterol carried in the blood — and in particular a high level of LDL, or so-called “bad” cholesterol — significantly increase the risk for coronary heart disease and heart attack. It is also well established that reducing cholesterol to achieve optimal levels can significantly reduce the risk of heart attacks and strokes.

Who is at risk of having a heart attack? EVERYONE. Heart disease is the NUMBER ONE killer of BOTH men AND women.

LDL cholesterol, HDL cholesterol, and triglycerides — are not the only risk factors for coronary heart disease. The risk increases with age, and if you also have a family history of premature heart disease, or are obese, smoke, have high blood pressure, or suffer from diabetes. Any decision about treating your cholesterol should be made in consultation with your doctor, taking all these heart disease and heart attack risk factors into account.

Whatever your heart health risk factors are, information is your best weapon in the fight against heart disease. Now is the time for you to re-evaluate whether you need to reduce your cholesterol.

In this free Johns Hopkins Special Report Seven Keys to Reduce Cholesterol, you will learn seven effective, proven, practical keys for lowering cholesterol-with the latest, best information and advice direct from Johns Hopkins, ranked #1 of America’s Best Hospitals for 16 consecutive years.

These keys include knowing your optimal cholesterol levels, diet, how to boost your HDL, whether statins can benefit you personally, and the latest news on “Combo Therapy” in treating cholesterol.

Written by two of the leading specialists at Johns Hopkins Medicine, Dr Simeon Margolis, Medical Editor of The Johns Hopkins Medical Letter: Health After 50 and Johns Hopkins White Papers for nearly two decades, and Dr. Roger S. Blumenthal, the Director of Johns Hopkins’ renowned Ciccarone Center for the Prevention of Heart Disease, Seven Keys to Reduce Cholesterol presents the latest medical research on the dangers of high cholesterol, and provides a powerful range of effective strategies for lowering your cholesterol safely.

Table of Contents: Seven Keys to Reduce Cholesterol

1-Know Your “Target” Cholesterol Levels

2-Focus on the Right Fats

3-Make the Most of Cholesterol-Busting Foods

4-Reduce Cholesterol with Medication

5-Consider “Combo Therapy” to Reduce Cholesterol

6-Boost Your HDL Cholesterol for Multiple Benefits

7-The ABCs of Heart Attack Prevention

Anyone wishing to receive Seven Keys to Reduce Cholesterol can visit the website Hopkins Reports: 7 Keys to Reduce Cholesterol http://www.hopkinsreports.com/cholesterol to download this invaluable Special Report.

The Johns Hopkins Special Reports website is produced by University Health Publishing, in conjunction with Johns Hopkins Medicine. University Health Publishing has been publishing branded Johns Hopkins University health-related information for people over 50 since 1988 through the monthly newsletter Johns Hopkins Medical Letter: Health After 50 and the Johns Hopkins White Papers.

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