HomeQuinaprilI take lisinopril, an ACE inhibitor. Alternatives? Grunting/clearing throat issues…?
Posted in Quinapril on 9th June 2014

I take lisinopril, an ACE inhibitor. Alternatives? Grunting/clearing throat issues…?
I take lisinopril, an ACE inhibitor, and I’m looking for alternatives. I constantly have to grunt/feel the need to clear my throat, and it’s driving me and other people around me. Essentially, I want the blood-pressure-lowering benefits, but not the side effects of a dry/itchy throat. Cough drops work for a time, but I’m looking for an alternative medication-based solution.
One responder described ARB as a class of drugs that are an alternative. Does anyone happen to know the drugs that would be included as ARB-class drugs?

Best answer(s):

Answer by ckm1956
Ask your doc if the symptoms are related. If so a drug class called “ARB” gives the same benefits with less side effects.

Answer by matador 89
Me Me,
This chain of blood pressure regulating hormones is referred to as the renin-angiotensin-aldosterone (RAA) hormonal system. The RAA system has long been known to be important in regulating the blood pressure in the body. Two classes of drugs have the most substantial effects on the RAA system. These two classes are the angiotensin receptor blockers (ARB drugs) and the angiotensin converting enzyme inhibitors – ACE inhibitors. Both of these classes of drugs lower blood pressure by blocking certain specific steps in the RAA chain. Very briefly, the ARB drugs block the chemical receptors for angiotensin II on the small arteries (arterioles). Therefore, the angiotensin cannot cause these arteries to constrict, which lowers the blood pressure. When the small arteries are constricted, they become stiff and narrow, which elevates the blood pressure. By blocking the action of angiotensin II on the small arteries, the ARB drugs prevent them from narrowing (constricting). The effect is to widen the arteries, which lowers the blood pressure. The ACE inhibitors block the action of the angiotensin-converting enzyme in the lungs so that angiotensin I is not converted into angiotensin II. The production of this powerful blood vessel constrictor is thereby prevented. The blood vessels thus remain widened, which results in lowering of the blood pressure. I list some drugs under this category:- The ARBs include candesartan (Atacand), olmesartan (Benicar), losartan (Cozaar), valsartan (Diovan), irbesartan (Avapro), telmisartan (Micardis) and eprosartan (Teveten). The following is an alphabetical list of the ACE inhibitors that are available in the United States: Benazepril (Lotensin), Captopril (Capoten), Enalapril (Vasotec), Fosinopril (Monopril), Moexipril (Univasc), Perindopril(Aceon), Quinapril (Accupril), Ramipril (Altace), Trandolapril (Mavik). I have left your current medication until the end, for obvious reasons. Lisinopril (Prinivil, Zestril). As each patient has different case details, you should discuss the difficulties that you have with your present medication and seek your doctor’s advice on which medication to change to that would be suitable for your needs. Be aware that many side effects are seen with ARB and ACE medications. You would be advised to discuss any major concerns with your doctor before starting therapy.

ALL ANSWERS SHOULD BE THOROUGHLY RESEARCHED, IN ANY FORUM AND ESPECIALLY IN THIS ONE. – MANY ANSWERS ARE FLAWED.

It is extremely important to obtain an accurate diagnosis before trying to find a cure. Many diseases and conditions share common symptoms.

The information provided here should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed physician should be consulted for diagnosis and treatment of any and all medical conditions.

Hope this helps
matador 89

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