What is in grapefruit that react with medications (cholesterol) makes?

What is in grapefruit that react with medications (cholesterol)? makes my father said he can not he is grapefruit because of its cholesterol drug B...


What is in grapefruit that react with medications (cholesterol)? makes
my father said he can not he is grapefruit because of its cholesterol drug Best Answer (s):

response from Srimathi
Grape fruit is good for lowering cholesterol, one should not take this fruit along with cholesterol medicine, it will have many side effects …

Reply gentle soul
drugs by grapefruit juice [17] affected grapefruit and grapefruit juice have the potential to interact with numerous drugs. Interfere with a variety of organic compounds such as furanocoumarin derivatives identified by the liver and intestinal cytochrome P450 enzyme isoform CYP3A4 and thus are responsible for the interaction in the first place. However, bioactive grapefruit juice may also P-glycoprotein and organic anion transporting polypeptides (OATPs) either increasing or decreasing bioavailability of a number of drugs interfere. Pomelo (the Asian fruit which was crossed with an orange to grapefruit) also contains large amounts of furanocoumarin derivatives drugs by grapefruit juice [17] affected drug class major Interaction Minor interaction calcium channel antagonistsPlendilCardene (nicardipine), Procardia (nifedipine) NimotopKonsularischenDynacircAntiarrhythmicsCordaroneDronedaronStatine (HMG-CoA reductase inhibitors), Mevacor (lovastatin) LipitorBaycol (from the market) ImmunosuppressantsSandimmune (cyclosporine) PrografRapamuneMercaptopurineDissociativesDextromethorphanSedativa, hypnotics and anxiolyticsBusparHalcionVersiertValium (diazepam) Sonata (zaleplon) AlprazolamAndere psychotropicsTegretol (carbamazepine) DesyrelSerzoneSeroquelFluvoxaminAntihistaminesSeldane (from the market), diphenhydramine (partially) Hismanal (from the market) Claritin (loratadine) HIV protease inhibitorsInviraseNorvirViraceptAgeneraseHormonesOrtho-CEPT (ethinyl estradiol) Depo-Medrol (methylprednisolone) Other drugsViagraPropulsid [18] [edit] drugs by grapefruit juice [17] affected drug class major Interaction Minor interaction calcium channel antagonistsPlendilCardene (nicardipine), Procardia (nifedipine) NimotopKonsularischenDynacircAntiarrhythmicsCordaroneDronedaronStatine (HMG-CoA reductase inhibitors), Mevacor (lovastatin) LipitorBaycol (from the market) ImmunosuppressantsSandimmune (cyclosporine) PrografRapamuneMercaptopurineDissociativesDextromethorphanSedativa, hypnotics and anxiolyticsBusparHalcionVersiertValium (diazepam) Sonata (zaleplon) AlprazolamAndere psychotropicsTegretol (carbamazepine) DesyrelSerzoneSeroquelFluvoxaminAntihistaminesSeldane (from the market), diphenhydramine (partially) Hismanal (from the market) Claritin ( loratadine) HIV protease inhibitorsInviraseNorvirViraceptAgeneraseHormonesOrtho-CEPT (ethinyl estradiol) Depo-Medrol (methylprednisolone) Other drugsViagraPropulsid [18] [edit]

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